Secondment  – WP6: numerical simulations of immune response

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The secondment of Luca Presotto from Università degli Studi di Milano-Bicocca to Uri Nevo’s lab at Tel Aviv University (TAU) is completed and has reached significant outcomes!
The objective of the secondment was to work on network analysis to immune reactions induced by the presence of biomaterials on macrophages, within the actions of WP6 (numerical simulations of immune response).
The knowledge of the molecular intracellular pathways triggered in these cells of the innate immune reaction is rapidly increasing. Indeed, we miss the possibility of extensive numerical simulations of the immune response based on agent-based modeling because of enormous complexity of the molecular machinery.
The work done in these months at TAU was to set the basis for a successful down-sizing of the molecular intracellular interaction networks for being able to implement extensive numerical simulations based on agent-based modeling.

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