Partner Politecnico di Milano

2PP fabrication of microstructures and microlenses

Role in the project: scientific coordination of the ultrafast laser setup and non-linear polymerization experiments.
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Role in the project: coordination of the bioengineering team; scientific supervision of the work concerning device design and development, validation in vitro and in vivo on chicken embryos.
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role in the project: in-vitro experiments on the immune reaction induced by the microstructures
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role in the project: microfabrication of microstructures and assembly of In2Sight.
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Main Task

  • Design of the platform
  • Microfluidic characterization
  • Cell repopulation studies in vitro
  • In vivo validation in all the main phases

Partner Description

The Politecnico di Milano, POLIMI, is the leading technical university in Italy. It is in the top ten list of the engineering and technology universities in Europe and between the first 30 in the world in the QS World University Rankings.

The ultrafast photonics team, based in the Physics Department (https://www.fisi.polimi.it/en), has an established track record in the generation of femtosecond light pulses and their applications to microstructuring of materials. The group was one of the pioneers of femtosecond laser waveguide writing in glasses, achieving seminal results such as the first waveguides mode-matched with single-mode optical fibers and the first waveguide lasers in rare-earth-doped glasses.

The bioengineering team is based at the Department of Chemistry, Materials and Chemical Engineering by Giulio Natta. Two different research laboratories will be involved in the project, namely the Mechanobiology lab, and the Live Cell Imaging lab, with expertise in the development of frontier tools for research in biology, such as nanoengineered stem cell niches, microfluidic bioreactors and miniaturized windows for imaging in live animals.

 

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